DNA Next-Generation Sequencer

The HTG EdgeSeq system simplifies gene expression profiling.
The HTG EdgeSeq processor, assays, and parser software facilitate analysis of gene expression profiles from a wide variety of specimen types to accelerate discovery, support translational applications and evaluate target biomarkers for companion diagnostics.

Our extraction-free specimen preparation and quantitative nuclease protection chemistry assays automate preparation of mRNA and miRNA targets for library preparation and next-generation sequencing (NGS) analysis.

HTG's solutions enable fast, reliable, reproducible, and quantitative analysis of thousands of targeted RNAs from a single assay in as little as 36 hours with reduced hands-on time from sample prep through data analysis.

Features
Automation solutions quickly and reliably generate gene expression profiles
Multiplex hundreds or thousands of different targets in a single reaction
Simplifies NGS-based workflow
Eliminates technically challenging steps for reduced hands-on time
Intuitive graphic user interface and simple data analysis

Workflow
HTG‘s extraction-free chemistry reduces sample input requirements and preserves valuable specimens. The HTG EdgeSeq chemistry eliminates timely and technically challenging steps - cDNA synthesis, size selection, rRNA depletion, end repair, and adapter ligation. HTG leverages the power of NGS and yields aligned data that accurately and reproducibly quantitates gene expression profiles.