Biosigma SPA. We are an Italian company leader in the production of disposable in plastic for Biotech and Life Science such as 2D-coded sample storage tubes and accessories. Our CryoGen ware is designed to meet the demands of liquid nitrogen temperatures and produced using rigorously tested materials. Our CryoGen tubes and Cryogen Boxes can withstand the extremes of cryogenic conditions while protecting your valuable samples. We select only high quality and purity virgin raw material to manufacture our cryoware. Our CLEARLine range doas also includes CLEARLock microtubes 0.5, 1.5, 2 and 5 ml with safety lock cap, MCT external screw cap microtubes, serological pipettes and 15/50 ml centrifuge tubes We are ISO13485, ISO14001, UNI ISO 45001:2018 cerified FDA resistered. Integrity.Be greenTrust.Accountable.Commitment to Customers.Passion.